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Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation
Methylene blue (MB), which has antioxidant, anti-inflammatory, neuroprotective, and mitochondria protective effects, has been widely used as a dye and medication. However, the effect of MB on inflammasome activation has not yet been studied. Inflammasomes are multi-protein complexes that induce matu...
Autores principales: | Ahn, Huijeong, Kang, Seung Goo, Yoon, Sung-il, Ko, Hyun-Jeong, Kim, Pyeung-Hyeun, Hong, Eui-Ju, An, Beum-Soo, Lee, Eunsong, Lee, Geun-Shik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622101/ https://www.ncbi.nlm.nih.gov/pubmed/28963531 http://dx.doi.org/10.1038/s41598-017-12635-6 |
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