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Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes

Functional beta cell mass is an essential biomarker for the diagnosis and staging of diabetes. It has however proven technically challenging to study this parameter during diabetes progression. Here we have detailed the kinetics of the rapid decline in functional beta cell mass in the RIP-DTR mouse,...

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Detalles Bibliográficos
Autores principales: van Krieken, Pim P., Dicker, Andrea, Eriksson, Maria, Herrera, Pedro L., Ahlgren, Ulf, Berggren, Per-Olof, Ilegems, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622115/
https://www.ncbi.nlm.nih.gov/pubmed/28963457
http://dx.doi.org/10.1038/s41598-017-12124-w