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BACE1-Dependent Neuregulin-1 Signaling: An Implication for Schizophrenia

Schizophrenia is a chronic psychiatric disorder with a lifetime prevalence of about 1% in the general population. Recent studies have shown that Neuregulin-1 (Nrg1) is a candidate gene for schizophrenia. At least 15 alternative splicing of NRG1 isoforms all contain an extracellular epidermal growth...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengrong, Huang, Jing, Shen, Yong, Li, Rena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622153/
https://www.ncbi.nlm.nih.gov/pubmed/28993723
http://dx.doi.org/10.3389/fnmol.2017.00302