Therapeutic Potential of Shark Anti-ICOSL VNAR Domains is Exemplified in a Murine Model of Autoimmune Non-Infectious Uveitis

Induced costimulatory ligand (ICOSL) plays an important role in the activation of T cells through its interaction with the inducible costimulator, ICOS. Suppression of full T cell activation can be achieved by blocking this interaction and has been shown to be an effective means of ameliorating dise...

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Detalles Bibliográficos
Autores principales: Kovaleva, Marina, Johnson, Katherine, Steven, John, Barelle, Caroline J., Porter, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622306/
https://www.ncbi.nlm.nih.gov/pubmed/28993766
http://dx.doi.org/10.3389/fimmu.2017.01121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622306/
https://www.ncbi.nlm.nih.gov/pubmed/28993766
http://dx.doi.org/10.3389/fimmu.2017.01121

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