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Preferential microRNA targeting revealed by in vivo competitive binding and differential Argonaute immunoprecipitation
MicroRNAs (miRNAs) have been described to simultaneously inhibit hundreds of targets, albeit to a modest extent. It was recently proposed that there could exist more specific, exceptionally strong binding to a subgroup of targets. However, it is unknown, whether this is the case and how such targets...
Autores principales: | Werfel, Stanislas, Leierseder, Simon, Ruprecht, Benjamin, Kuster, Bernhard, Engelhardt, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622317/ https://www.ncbi.nlm.nih.gov/pubmed/28973447 http://dx.doi.org/10.1093/nar/gkx640 |
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