The Procoagulant Activity of Apoptotic Cells Is Mediated by Interaction with Factor XII

Apoptotic cells, by externalizing phosphatidylserine (PS) as a hallmark feature, are procoagulant. However, the mechanism by which apoptotic cells activate coagulation system remains unknown. Intrinsic coagulation pathway is initiated by coagulation factor XII (FXII) of contact activation system. Th...

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Detalles Bibliográficos
Autores principales: Yang, Aizhen, Chen, Fengwu, He, Chao, Zhou, Junsong, Lu, Yi, Dai, Jihong, Birge, Raymond B., Wu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622377/
https://www.ncbi.nlm.nih.gov/pubmed/28993777
http://dx.doi.org/10.3389/fimmu.2017.01188

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