Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks

BACKGROUND: Human fibroblasts can be directly converted to several subtypes of neurons, but cortical projection neurons have not been generated. METHODS: Here we screened for transcription factor combinations that could potentially convert human fibroblasts to functional excitatory cortical neurons....

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Detalles Bibliográficos
Autores principales: Miskinyte, Giedre, Devaraju, Karthikeyan, Grønning Hansen, Marita, Monni, Emanuela, Tornero, Daniel, Woods, Niels Bjarne, Bengzon, Johan, Ahlenius, Henrik, Lindvall, Olle, Kokaia, Zaal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622454/
https://www.ncbi.nlm.nih.gov/pubmed/28962665
http://dx.doi.org/10.1186/s13287-017-0658-3

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