Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

BACKGROUND: Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets. METHODS: Human MSC and human islets (or pseudoislets, obtained...

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Detalles Bibliográficos
Autores principales: Montanari, Elisa, Meier, Raphael P. H., Mahou, Redouan, Seebach, Jörg D., Wandrey, Christine, Gerber-Lemaire, Sandrine, Buhler, Leo H., Gonelle-Gispert, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622460/
https://www.ncbi.nlm.nih.gov/pubmed/28962589
http://dx.doi.org/10.1186/s13287-017-0646-7

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