Cargando…

Neuro-protective effect of rutin against Cisplatin-induced neurotoxic rat model

BACKGROUND: Cisplatin is widely used chemotherapeutic agent for cancer treatment with limited uses due to its neurotoxic side effect. The aim of this study was to determine the potential preventive effects of rutin on the brain of cisplatin- neurotoxic rat model. METHODS: Forty rats were divided int...

Descripción completa

Detalles Bibliográficos
Autores principales:	Almutairi, Mashal M., Alanazi, Wael A., Alshammari, Musaad A., Alotaibi, Moureq Rashed, Alhoshani, Ali R., Al-Rejaie, Salim Salah, Hafez, Mohamed M., Al-Shabanah, Othman A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622464/ https://www.ncbi.nlm.nih.gov/pubmed/28962559 http://dx.doi.org/10.1186/s12906-017-1976-9

Ejemplares similares

Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats
por: Alhoshani, Ali R., et al.
Publicado: (2017)

Inhibitory Effect of Ginseng on Breast Cancer Cell Line Growth Via Up-Regulation of Cyclin Dependent Kinase Inhibitor, p21 and p53
por: AL Shabanah, Othman A, et al.
Publicado: (2016)

Characterization of Apoptosis in a Breast Cancer Cell Line after IL-10 Silencing
por: Alotaibi, Moureq R, et al.
Publicado: (2018)

Hepato-protective effect of rutin via IL-6/STAT3 pathway in CCl(4)-induced hepatotoxicity in rats
por: Hafez, Mohamed M., et al.
Publicado: (2015)

Protective effect of rutin on the antioxidant genes expression in hypercholestrolemic male Westar rat
por: Al-Rejaie, Salem S, et al.
Publicado: (2013)

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
por: Alanazi, Fawaz E., et al.
Publicado: (2022)

Effect of Autophagy Inhibitors on Radiosensitivity in DNA Repair-Proficient and -Deficient Glioma Cells
por: Saleh, Tareq, et al.
Publicado: (2022)

Rutin Attenuates Hepatotoxicity in High-Cholesterol-Diet-Fed Rats
por: AlSharari, Shakir D., et al.
Publicado: (2016)

Neuroinflammatory Cytokines Induce Amyloid Beta Neurotoxicity through Modulating Amyloid Precursor Protein Levels/Metabolism
por: Alasmari, Fawaz, et al.
Publicado: (2018)

Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling
por: Sayed-Ahmed, Mohamed M, et al.
Publicado: (2010)

Effects of rutin on acrylamide-induced neurotoxicity
por: Motamedshariaty, Vahideh Sadat, et al.
Publicado: (2014)

Effect of ginseng extract on the TGF-β1 signaling pathway in CCl(4)-induced liver fibrosis in rats
por: Hafez, Mohamed M., et al.
Publicado: (2017)

Association between Paraoxonases Gene Expression and Oxidative Stress in Hepatotoxicity Induced by CCl(4)
por: Hafez, Mohamed M., et al.
Publicado: (2014)

A newly synthesized platinum-based compound (PBC-II) increases chemosensitivity of HeLa ovarian cancer cells via inhibition of autophagy
por: Alotaibi, Moureq Rashed, et al.
Publicado: (2019)

Desferrioxamine Attenuates Doxorubicin-Induced Acute Cardiotoxicity through TFG-β/Smad p53 Pathway in Rat Model
por: Al-Shabanah, Othman A., et al.
Publicado: (2012)

Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells
por: As Sobeai, Homood M., et al.
Publicado: (2022)

In vivo and in vitro studies evaluating the chemopreventive effect of metformin on the aryl hydrocarbon receptor-mediated breast carcinogenesis
por: Alhoshani, Ali, et al.
Publicado: (2021)

Human papillomavirus genotyping and integration in ovarian cancer Saudi patients
por: Al-Shabanah, Othman A, et al.
Publicado: (2013)

Liraglutide attenuates gefitinib-induced cardiotoxicity and promotes cardioprotection through the regulation of MAPK/NF-κB signaling pathways
por: AlAsmari, Abdullah F., et al.
Publicado: (2020)

The Combination of Radiation with PARP Inhibition Enhances Senescence and Sensitivity to the Senolytic, Navitoclax, in Triple Negative Breast Tumor Cells
por: Softah, Abrar, et al.
Publicado: (2023)

Nicotine and cotinine quantification after a 4-week inhalation of electronic cigarette vapors in male and female mice using UPLC-MS/MS
por: Alasmari, Fawaz, et al.
Publicado: (2022)

Metallothionein induction reduces caspase-3 activity and TNFα levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated rats
por: Helal, Gouda K, et al.
Publicado: (2009)

Alleviation of cisplatin-induced neuropathic pain, neuronal apoptosis, and systemic inflammation in mice by rapamycin
por: Alotaibi, Moureq, et al.
Publicado: (2022)

Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats
por: Al-Rejaie, Salim Salih, et al.
Publicado: (2012)

Downregulation of Oxidative and Nitrosative Apoptotic Signaling by L-Carnitine in Ifosfamide-Induced Fanconi Syndrome Rat Model
por: Sayed-Ahmed, Mohamed M., et al.
Publicado: (2012)

Anti-metastatic and anti-proliferative activity of eugenol against triple negative and HER2 positive breast cancer cells
por: Abdullah, Mashan L., et al.
Publicado: (2018)

Coadministration of Ketamine and Perampanel Improves Behavioral Function and Reduces Inflammation in Acute Traumatic Brain Injury Mouse Model
por: Alqahtani, Faleh, et al.
Publicado: (2020)

Synthesis, Characterization, and Anticancer Activity of Phosphanegold(i) Complexes of 3-Thiosemicarbano-butan-2-one Oxime
por: Zarewa, Sani A., et al.
Publicado: (2023)

Eugenol-Induced Autophagy and Apoptosis in Breast Cancer Cells via PI3K/AKT/FOXO3a Pathway Inhibition
por: Abdullah, Mashan L., et al.
Publicado: (2021)

Inhibition of Gene Expression of Organic Cation/Carnitine Transporter and Antioxidant Enzymes in Oxazaphosphorines-Induced Acute Cardiomyopathic Rat Models
por: Sayed-Ahmed, Mohamed M., et al.
Publicado: (2012)

The attitude and practice of general surgeons toward cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A cross-sectional study
por: Bin Traiki, Thamer A., et al.
Publicado: (2021)

Simultaneous Determination of Different Polyamines and their Mono-Acetylated Derivatives in Gastric Tissue by HPLC with Post-Column Derivatization
por: Raza, Muhammad, et al.
Publicado: (2010)

Effects of Chronic Inhalation of Electronic Cigarette Vapor Containing Nicotine on Neurobehaviors and Pre/Postsynaptic Neuron Markers
por: Alasmari, Fawaz, et al.
Publicado: (2022)

Doxorubicin Toxicity can be Ameliorated during Antioxidant L-Carnitine Supplementation
por: Alshabanah, Othman A., et al.
Publicado: (2010)

Angiotensin II type 1 receptor blockade attenuates gefitinib-induced cardiac hypertrophy via adjusting angiotensin II-mediated oxidative stress and JNK/P38 MAPK pathway in a rat model
por: Alanazi, Wael A., et al.
Publicado: (2022)

Anticancer Activity and Apoptosis Induction of Gold(III) Complexes Containing 2,2′-Bipyridine-3,3′-dicarboxylic Acid and Dithiocarbamates
por: Alhoshani, Ali, et al.
Publicado: (2021)

Carnitine Supplementation Attenuates Sunitinib-Induced Inhibition of AMP-Activated Protein Kinase Downstream Signals in Cardiac Tissues
por: Sayed-Ahmed, Mohamed M., et al.
Publicado: (2019)

Syndrome of Irreversible Lithium-Effectuated NeuroToxicity: SILENT, but not innocent
por: Bicho, M. S., et al.
Publicado: (2023)

Improving the understanding of originator and biosimilar biologics among healthcare providers in Saudi Arabia
por: Omair, Mohammed A., et al.
Publicado: (2020)

Memantine Attenuates Cocaine and neuroHIV Neurotoxicity in the Medial Prefrontal Cortex
por: Du, Congwu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f4r2tigebji6n9bu284tcil10p