A novel mechanism of lncRNA and miRNA interaction: CCAT2 regulates miR-145 expression by suppressing its maturation process in colon cancer cells

BACKGROUND: Although both long and micro RNAs are emerging as important functional components in colorectal cancer (CRC) progression and metastasis, the mechanism of their interaction remains poorly understood. CCAT2 (Colon cancer-associated transcript-2), a long noncoding RNA (lncRNA), has been rep...

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Detalles Bibliográficos
Autores principales: Yu, Yingjie, Nangia-Makker, Pratima, Farhana, Lulu, Majumdar, Adhip P. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622467/
https://www.ncbi.nlm.nih.gov/pubmed/28964256
http://dx.doi.org/10.1186/s12943-017-0725-5

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