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The potential role of miRNAs in therapy of breast and ovarian cancers associated with BRCA1 mutation
Germline variants within BRCA1 or BRCA2 genes account for approximately 25% of familial aggregations of breast-ovarian cancers. Low or no expression of BRCA1 in breast and ovarian cancers is associated with a good clinical response to treatment with platinum therapies and PARP1 inhibitors. Recent st...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622493/ https://www.ncbi.nlm.nih.gov/pubmed/29021870 http://dx.doi.org/10.1186/s13053-017-0076-7 |