Local application of IGFBP5 protein enhanced periodontal tissue regeneration via increasing the migration, cell proliferation and osteo/dentinogenic differentiation of mesenchymal stem cells in an inflammatory niche

BACKGROUND: Periodontitis is a widespread infectious disease ultimately resulting in tooth loss. The number of mesenchymal stem cells (MSCs) in patients with periodontitis is decreased, and MSC functions are impaired. Rescuing the impaired function of MSCs in periodontitis is the key for treatment,...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Nannan, Zhang, Fengqiu, Li, Guoqing, Zhang, Xiuli, Lin, Xiao, Yang, Haoqing, Wang, Lijun, Cao, Yangyang, Du, Juan, Fan, Zhipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622495/
https://www.ncbi.nlm.nih.gov/pubmed/28962660
http://dx.doi.org/10.1186/s13287-017-0663-6

Ejemplares similares

Ejemplares similares