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Dietary and health biomarkers—time for an update

In the dietary and health research area, biomarkers are extensively used for multiple purposes. These include biomarkers of dietary intake and nutrient status, biomarkers used to measure the biological effects of specific dietary components, and biomarkers to assess the effects of diet on health. Th...

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Autores principales: Dragsted, Lars O., Gao, Qian, Praticò, Giulia, Manach, Claudine, Wishart, David S., Scalbert, Augustin, Feskens, Edith J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622518/
https://www.ncbi.nlm.nih.gov/pubmed/28974991
http://dx.doi.org/10.1186/s12263-017-0578-y
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author Dragsted, Lars O.
Gao, Qian
Praticò, Giulia
Manach, Claudine
Wishart, David S.
Scalbert, Augustin
Feskens, Edith J. M.
author_facet Dragsted, Lars O.
Gao, Qian
Praticò, Giulia
Manach, Claudine
Wishart, David S.
Scalbert, Augustin
Feskens, Edith J. M.
author_sort Dragsted, Lars O.
collection PubMed
description In the dietary and health research area, biomarkers are extensively used for multiple purposes. These include biomarkers of dietary intake and nutrient status, biomarkers used to measure the biological effects of specific dietary components, and biomarkers to assess the effects of diet on health. The implementation of biomarkers in nutritional research will be important to improve measurements of dietary intake, exposure to specific dietary components, and of compliance to dietary interventions. Biomarkers could also help with improved characterization of nutritional status in study volunteers and to provide much mechanistic insight into the effects of food components and diets. Although hundreds of papers in nutrition are published annually, there is no current ontology for the area, no generally accepted classification terminology for biomarkers in nutrition and health, no systematic validation scheme for these biomarker classes, and no recent systematic review of all proposed biomarkers for food intake. While advanced databases exist for the human and food metabolomes, additional tools are needed to curate and evaluate current data on dietary and health biomarkers. The Food Biomarkers Alliance (FoodBAll) under the Joint Programming Initiative—A Healthy Diet for a Healthy Life (JPI-HDHL)—is aimed at meeting some of these challenges, identifying new dietary biomarkers, and producing new databases and review papers on biomarkers for nutritional research. This current paper outlines the needs and serves as an introduction to this thematic issue of Genes & Nutrition on dietary and health biomarkers.
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spelling pubmed-56225182017-10-03 Dietary and health biomarkers—time for an update Dragsted, Lars O. Gao, Qian Praticò, Giulia Manach, Claudine Wishart, David S. Scalbert, Augustin Feskens, Edith J. M. Genes Nutr Commentary In the dietary and health research area, biomarkers are extensively used for multiple purposes. These include biomarkers of dietary intake and nutrient status, biomarkers used to measure the biological effects of specific dietary components, and biomarkers to assess the effects of diet on health. The implementation of biomarkers in nutritional research will be important to improve measurements of dietary intake, exposure to specific dietary components, and of compliance to dietary interventions. Biomarkers could also help with improved characterization of nutritional status in study volunteers and to provide much mechanistic insight into the effects of food components and diets. Although hundreds of papers in nutrition are published annually, there is no current ontology for the area, no generally accepted classification terminology for biomarkers in nutrition and health, no systematic validation scheme for these biomarker classes, and no recent systematic review of all proposed biomarkers for food intake. While advanced databases exist for the human and food metabolomes, additional tools are needed to curate and evaluate current data on dietary and health biomarkers. The Food Biomarkers Alliance (FoodBAll) under the Joint Programming Initiative—A Healthy Diet for a Healthy Life (JPI-HDHL)—is aimed at meeting some of these challenges, identifying new dietary biomarkers, and producing new databases and review papers on biomarkers for nutritional research. This current paper outlines the needs and serves as an introduction to this thematic issue of Genes & Nutrition on dietary and health biomarkers. BioMed Central 2017-09-29 /pmc/articles/PMC5622518/ /pubmed/28974991 http://dx.doi.org/10.1186/s12263-017-0578-y Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Dragsted, Lars O.
Gao, Qian
Praticò, Giulia
Manach, Claudine
Wishart, David S.
Scalbert, Augustin
Feskens, Edith J. M.
Dietary and health biomarkers—time for an update
title Dietary and health biomarkers—time for an update
title_full Dietary and health biomarkers—time for an update
title_fullStr Dietary and health biomarkers—time for an update
title_full_unstemmed Dietary and health biomarkers—time for an update
title_short Dietary and health biomarkers—time for an update
title_sort dietary and health biomarkers—time for an update
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622518/
https://www.ncbi.nlm.nih.gov/pubmed/28974991
http://dx.doi.org/10.1186/s12263-017-0578-y
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