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DAF-shielded baculovirus-vectored vaccine enhances protection against malaria sporozoite challenge in mice

BACKGROUND: Previous studies have shown that the baculovirus-vectored vaccine based on the “baculovirus dual expression system (BDES)” is an effective vaccine delivery platform for malaria. However, a point of weakness remaining for use of this vaccine platform in vivo concerns viral inactivation by...

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Detalles Bibliográficos
Autores principales: Iyori, Mitsuhiro, Yamamoto, Daisuke S., Sakaguchi, Miako, Mizutani, Masanori, Ogata, Sota, Nishiura, Hidesato, Tamura, Takahiko, Matsuoka, Hiroyuki, Yoshida, Shigeto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622557/
https://www.ncbi.nlm.nih.gov/pubmed/28962615
http://dx.doi.org/10.1186/s12936-017-2039-x