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Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1

Stimulation of the ubiquitin-proteasome pathway—especially E3 ubiquitin ligases Atrogin-1 and MuRF1—is associated with muscle loss in diabetes. Elevated lipid metabolites impair myogenesis. Oligonol, a low molecular weight polyphenol derived from lychee, exhibited anti-diabetic and anti-obesity prop...

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Detalles Bibliográficos
Autores principales:	Liu, Hung-Wen, Chen, Yen-Ju, Chang, Yun-Ching, Chang, Sue-Joan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622800/ https://www.ncbi.nlm.nih.gov/pubmed/28930190 http://dx.doi.org/10.3390/nu9091040

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