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Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case

Parathyroid carcinomas are rare endocrine tumors which comprise 0.3-5.6% of all causes of hyperparathyroidism. 90% of them are hormonally active, while 10% of them may be non-functional. They mostly occur in a single parathyroid gland. Concurrent involvement of both parathyroid glands is quite rare....

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Autores principales: Dikmen, Kursat, Bostanci, Hasan, Gobut, Huseyin, Yildiz, Alp, Ertunc, Onur, Celik, Ali, Akin, Murat, Taneri, Ferit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622813/
https://www.ncbi.nlm.nih.gov/pubmed/28979642
http://dx.doi.org/10.11604/pamj.2017.27.241.11503
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author Dikmen, Kursat
Bostanci, Hasan
Gobut, Huseyin
Yildiz, Alp
Ertunc, Onur
Celik, Ali
Akin, Murat
Taneri, Ferit
author_facet Dikmen, Kursat
Bostanci, Hasan
Gobut, Huseyin
Yildiz, Alp
Ertunc, Onur
Celik, Ali
Akin, Murat
Taneri, Ferit
author_sort Dikmen, Kursat
collection PubMed
description Parathyroid carcinomas are rare endocrine tumors which comprise 0.3-5.6% of all causes of hyperparathyroidism. 90% of them are hormonally active, while 10% of them may be non-functional. They mostly occur in a single parathyroid gland. Concurrent involvement of both parathyroid glands is quite rare. A 57-year-old male patient was admitted to emergency department with the complaint of dyspnea. Thorax tomography revealed a retrosternal mass. The mass was thoracoscopically excised by thoracic surgeons. Histopathological examination result of the mass was reported as parathyroid carcinoma. Parathyroid scintigraphy performed and focal activity increase in the lower pole of the left lobe. Parathyroid hormone level was 118 pg/ml and calcium level was measured as 11.4 mg/dl. The patient with these findings was operated and pathological examination of excised left lower parathyroid tissue was reported as carcinoma. In addition, micropapillary carcinoma was detected in left thyroid lobectomy specimen.Our case was also unusual in that double parathyroid carcinoma, which is a rare condition, was hormonally inactive. We aimed to present our case in the light of the literature due to its rare occurrence.
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spelling pubmed-56228132017-10-04 Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case Dikmen, Kursat Bostanci, Hasan Gobut, Huseyin Yildiz, Alp Ertunc, Onur Celik, Ali Akin, Murat Taneri, Ferit Pan Afr Med J Case Report Parathyroid carcinomas are rare endocrine tumors which comprise 0.3-5.6% of all causes of hyperparathyroidism. 90% of them are hormonally active, while 10% of them may be non-functional. They mostly occur in a single parathyroid gland. Concurrent involvement of both parathyroid glands is quite rare. A 57-year-old male patient was admitted to emergency department with the complaint of dyspnea. Thorax tomography revealed a retrosternal mass. The mass was thoracoscopically excised by thoracic surgeons. Histopathological examination result of the mass was reported as parathyroid carcinoma. Parathyroid scintigraphy performed and focal activity increase in the lower pole of the left lobe. Parathyroid hormone level was 118 pg/ml and calcium level was measured as 11.4 mg/dl. The patient with these findings was operated and pathological examination of excised left lower parathyroid tissue was reported as carcinoma. In addition, micropapillary carcinoma was detected in left thyroid lobectomy specimen.Our case was also unusual in that double parathyroid carcinoma, which is a rare condition, was hormonally inactive. We aimed to present our case in the light of the literature due to its rare occurrence. The African Field Epidemiology Network 2017-08-02 /pmc/articles/PMC5622813/ /pubmed/28979642 http://dx.doi.org/10.11604/pamj.2017.27.241.11503 Text en © Kursat Dikmen et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dikmen, Kursat
Bostanci, Hasan
Gobut, Huseyin
Yildiz, Alp
Ertunc, Onur
Celik, Ali
Akin, Murat
Taneri, Ferit
Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case
title Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case
title_full Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case
title_fullStr Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case
title_full_unstemmed Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case
title_short Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case
title_sort nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622813/
https://www.ncbi.nlm.nih.gov/pubmed/28979642
http://dx.doi.org/10.11604/pamj.2017.27.241.11503
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