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Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon
INTRODUCTION: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created h...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The African Field Epidemiology Network
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622837/ https://www.ncbi.nlm.nih.gov/pubmed/28979637 http://dx.doi.org/10.11604/pamj.2017.27.235.13121 |
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author | Luma, Henry Namme Halle, Marie Patrice Eloumou, Servais Albert Fiacre Bagnaka Azingala, Fondong Kamdem, Felicite Donfack-Sontsa, Olivier Ashuntantang, Gloria |
author_facet | Luma, Henry Namme Halle, Marie Patrice Eloumou, Servais Albert Fiacre Bagnaka Azingala, Fondong Kamdem, Felicite Donfack-Sontsa, Olivier Ashuntantang, Gloria |
author_sort | Luma, Henry Namme |
collection | PubMed |
description | INTRODUCTION: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created haemodialysis units in Cameroon: the Buea and Bamenda haemodialysis centres. METHODS: A cross sectional study: included were patients who had spent at least three months in haemodialysis. HBV, HCV and HIV serologies were determined and patients' characteristics extracted from patient's records. RESULTS: We included 104 participants (44 in Buea and 60 in Bamenda). Mean age was 48 years and 65.4% were men. Median duration in dialysis was 14 months. One of the three viral markers was present in 40.1% of patients. The hepatitis B surface antigen, anti-HCV and anti-HIV antibody prevalence were respectively 10.6%, 19.2%, 13.5%. A history of sexually transmitted infection was the only variable associated with anti-HIV antibody positivity CONCLUSION: The sero-prevalence of HBsAg, HCV and HIV are high in the two centres. HIV prevalence may have reflected its etiology as a cause of ESKD. HCV remains a cause for concern and needs further evaluation. There is urgent need for the implementation of preventive and control measures. |
format | Online Article Text |
id | pubmed-5622837 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-56228372017-10-04 Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon Luma, Henry Namme Halle, Marie Patrice Eloumou, Servais Albert Fiacre Bagnaka Azingala, Fondong Kamdem, Felicite Donfack-Sontsa, Olivier Ashuntantang, Gloria Pan Afr Med J Research INTRODUCTION: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created haemodialysis units in Cameroon: the Buea and Bamenda haemodialysis centres. METHODS: A cross sectional study: included were patients who had spent at least three months in haemodialysis. HBV, HCV and HIV serologies were determined and patients' characteristics extracted from patient's records. RESULTS: We included 104 participants (44 in Buea and 60 in Bamenda). Mean age was 48 years and 65.4% were men. Median duration in dialysis was 14 months. One of the three viral markers was present in 40.1% of patients. The hepatitis B surface antigen, anti-HCV and anti-HIV antibody prevalence were respectively 10.6%, 19.2%, 13.5%. A history of sexually transmitted infection was the only variable associated with anti-HIV antibody positivity CONCLUSION: The sero-prevalence of HBsAg, HCV and HIV are high in the two centres. HIV prevalence may have reflected its etiology as a cause of ESKD. HCV remains a cause for concern and needs further evaluation. There is urgent need for the implementation of preventive and control measures. The African Field Epidemiology Network 2017-07-31 /pmc/articles/PMC5622837/ /pubmed/28979637 http://dx.doi.org/10.11604/pamj.2017.27.235.13121 Text en © Henry Namme Luma et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Luma, Henry Namme Halle, Marie Patrice Eloumou, Servais Albert Fiacre Bagnaka Azingala, Fondong Kamdem, Felicite Donfack-Sontsa, Olivier Ashuntantang, Gloria Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon |
title | Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon |
title_full | Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon |
title_fullStr | Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon |
title_full_unstemmed | Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon |
title_short | Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon |
title_sort | seroprevalence of human immunodeficiency virus, hepatitis b and c viruses among haemodialysis patients in two newly opened centres in cameroon |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622837/ https://www.ncbi.nlm.nih.gov/pubmed/28979637 http://dx.doi.org/10.11604/pamj.2017.27.235.13121 |
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