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Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon

INTRODUCTION: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created h...

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Autores principales: Luma, Henry Namme, Halle, Marie Patrice, Eloumou, Servais Albert Fiacre Bagnaka, Azingala, Fondong, Kamdem, Felicite, Donfack-Sontsa, Olivier, Ashuntantang, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622837/
https://www.ncbi.nlm.nih.gov/pubmed/28979637
http://dx.doi.org/10.11604/pamj.2017.27.235.13121
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author Luma, Henry Namme
Halle, Marie Patrice
Eloumou, Servais Albert Fiacre Bagnaka
Azingala, Fondong
Kamdem, Felicite
Donfack-Sontsa, Olivier
Ashuntantang, Gloria
author_facet Luma, Henry Namme
Halle, Marie Patrice
Eloumou, Servais Albert Fiacre Bagnaka
Azingala, Fondong
Kamdem, Felicite
Donfack-Sontsa, Olivier
Ashuntantang, Gloria
author_sort Luma, Henry Namme
collection PubMed
description INTRODUCTION: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created haemodialysis units in Cameroon: the Buea and Bamenda haemodialysis centres. METHODS: A cross sectional study: included were patients who had spent at least three months in haemodialysis. HBV, HCV and HIV serologies were determined and patients' characteristics extracted from patient's records. RESULTS: We included 104 participants (44 in Buea and 60 in Bamenda). Mean age was 48 years and 65.4% were men. Median duration in dialysis was 14 months. One of the three viral markers was present in 40.1% of patients. The hepatitis B surface antigen, anti-HCV and anti-HIV antibody prevalence were respectively 10.6%, 19.2%, 13.5%. A history of sexually transmitted infection was the only variable associated with anti-HIV antibody positivity CONCLUSION: The sero-prevalence of HBsAg, HCV and HIV are high in the two centres. HIV prevalence may have reflected its etiology as a cause of ESKD. HCV remains a cause for concern and needs further evaluation. There is urgent need for the implementation of preventive and control measures.
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spelling pubmed-56228372017-10-04 Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon Luma, Henry Namme Halle, Marie Patrice Eloumou, Servais Albert Fiacre Bagnaka Azingala, Fondong Kamdem, Felicite Donfack-Sontsa, Olivier Ashuntantang, Gloria Pan Afr Med J Research INTRODUCTION: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created haemodialysis units in Cameroon: the Buea and Bamenda haemodialysis centres. METHODS: A cross sectional study: included were patients who had spent at least three months in haemodialysis. HBV, HCV and HIV serologies were determined and patients' characteristics extracted from patient's records. RESULTS: We included 104 participants (44 in Buea and 60 in Bamenda). Mean age was 48 years and 65.4% were men. Median duration in dialysis was 14 months. One of the three viral markers was present in 40.1% of patients. The hepatitis B surface antigen, anti-HCV and anti-HIV antibody prevalence were respectively 10.6%, 19.2%, 13.5%. A history of sexually transmitted infection was the only variable associated with anti-HIV antibody positivity CONCLUSION: The sero-prevalence of HBsAg, HCV and HIV are high in the two centres. HIV prevalence may have reflected its etiology as a cause of ESKD. HCV remains a cause for concern and needs further evaluation. There is urgent need for the implementation of preventive and control measures. The African Field Epidemiology Network 2017-07-31 /pmc/articles/PMC5622837/ /pubmed/28979637 http://dx.doi.org/10.11604/pamj.2017.27.235.13121 Text en © Henry Namme Luma et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Luma, Henry Namme
Halle, Marie Patrice
Eloumou, Servais Albert Fiacre Bagnaka
Azingala, Fondong
Kamdem, Felicite
Donfack-Sontsa, Olivier
Ashuntantang, Gloria
Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon
title Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon
title_full Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon
title_fullStr Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon
title_full_unstemmed Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon
title_short Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon
title_sort seroprevalence of human immunodeficiency virus, hepatitis b and c viruses among haemodialysis patients in two newly opened centres in cameroon
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622837/
https://www.ncbi.nlm.nih.gov/pubmed/28979637
http://dx.doi.org/10.11604/pamj.2017.27.235.13121
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