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Rapamycin is highly effective in murine models of immune-mediated bone marrow failure

Acquired aplastic anemia, the prototypical bone marrow failure disease, is characterized by pancytopenia and marrow hypoplasia. Most aplastic anemia patients respond to immunosuppressive therapy, usually with anti-thymocyte globulin and cyclosporine, but some relapse on cyclosporine withdrawal or re...

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Detalles Bibliográficos
Autores principales: Feng, Xingmin, Lin, Zenghua, Sun, Wanling, Hollinger, Maile K., Desierto, Marie J., Keyvanfar, Keyvan, Malide, Daniela, Muranski, Pawel, Chen, Jichun, Young, Neal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622853/
https://www.ncbi.nlm.nih.gov/pubmed/28729300
http://dx.doi.org/10.3324/haematol.2017.163675