Cargando…

Impaired Cellular Energy Metabolism Contributes to Duck-Enteritis-Virus-Induced Autophagy via the AMPK–TSC2–MTOR Signaling Pathway

Duck enteritis virus (DEV) is a large, complex double-stranded DNA virus that induces duck embryo fibroblast (DEF) cells autophagy, which is beneficial to its own replication, but the mechanism has not been described. In this study, we showed that impaired cell energy metabolism is involved in DEV-i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Haichang, Zhao, Lili, Li, Siqi, Xu, Lijing, Wang, Yiping, Chen, Hongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622931/ https://www.ncbi.nlm.nih.gov/pubmed/29018776 http://dx.doi.org/10.3389/fcimb.2017.00423

Ejemplares similares

Duck enteritis virus activates CaMKKβ-AMPK to trigger autophagy in duck embryo fibroblast cells via increased cytosolic calcium
por: Yin, Haichang, et al.
Publicado: (2018)

Metagenomic Analysis of the Jinding Duck Fecal Virome
por: Zhao, Lili, et al.
Publicado: (2018)

Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells
por: Wang, Qing, et al.
Publicado: (2023)

Electroacupuncture Upregulated Ghrelin in Rats with Functional Dyspepsia via AMPK/TSC2/Rheb-Mediated mTOR Inhibition
por: Tang, Lei, et al.
Publicado: (2019)

Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy
por: Ganesan, Raja, et al.
Publicado: (2017)

AMPK–mTOR Signaling and Cellular Adaptations in Hypoxia
por: Chun, Yoomi, et al.
Publicado: (2021)

DEV induce autophagy via the endoplasmic reticulum stress related unfolded protein response
por: Yin, Haichang, et al.
Publicado: (2017)

The TSC-mTOR pathway regulates macrophage polarization
por: Byles, Vanessa, et al.
Publicado: (2013)

ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis
por: Xiong, Yuyan, et al.
Publicado: (2015)

Role of AMPK in autophagy
por: Wang, Shengyuan, et al.
Publicado: (2022)

WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy
por: Bakula, Daniela, et al.
Publicado: (2017)

Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway
por: Presneau, N, et al.
Publicado: (2009)

Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer
por: Mrozek, Evelyn M., et al.
Publicado: (2021)

Hyperbaric oxygen relieves neuropathic pain through AKT/TSC2/mTOR pathway activity to induce autophagy
por: Liu, Yong-Da, et al.
Publicado: (2019)

Downregulation of microRNA-30a-5p contributes to the replication of duck enteritis virus by regulating Beclin-1-mediated autophagy
por: Wu, Xianglong, et al.
Publicado: (2019)

lncRNA CASC19 Contributes to Radioresistance of Nasopharyngeal Carcinoma by Promoting Autophagy via AMPK-mTOR Pathway
por: Liu, Hongxia, et al.
Publicado: (2021)

BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain—Implications for Neurodegeneration
por: Lanzillotta, Chiara, et al.
Publicado: (2020)

The TSC1-TSC2 complex consists of multiple TSC1 and TSC2 subunits
por: Hoogeveen-Westerveld, Marianne, et al.
Publicado: (2012)

Thymol Alleviates LPS-Induced Liver Inflammation and Apoptosis by Inhibiting NLRP3 Inflammasome Activation and the AMPK-mTOR-Autophagy Pathway
por: Dou, Xiujing, et al.
Publicado: (2022)

TFEC contributes to cardiac hypertrophy by inhibiting AMPK/mTOR signaling
por: Zhao, Ting, et al.
Publicado: (2021)

Identification of an AMPK Phosphorylation Site in Drosophila TSC2 (gigas) that Regulate Cell Growth
por: Kim, Myungjin, et al.
Publicado: (2015)

Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway
por: Wang, Jiwei, et al.
Publicado: (2016)

Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats ulcerative colitis
por: Su, Shuai, et al.
Publicado: (2021)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Is mTOR Inhibitor Good Enough for Treatment All Tumors in TSC Patients?
por: Habib, Samy L, et al.
Publicado: (2016)

Autophagy Induction by Silibinin Positively Contributes to Its Anti-Metastatic Capacity via AMPK/mTOR Pathway in Renal Cell Carcinoma
por: Li, Feng, et al.
Publicado: (2015)

Topiramate Reprofiling for the Attenuation of Cadmium-Induced Testicular Impairment in Rats: Role of NLRP3 Inflammasome and AMPK/mTOR-Linked Autophagy
por: Arab, Hany H., et al.
Publicado: (2022)

Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway
por: Yang, Yang, et al.
Publicado: (2020)

AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation
por: Van Nostrand, Jeanine L., et al.
Publicado: (2020)

Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation
por: Fang, Yili, et al.
Publicado: (2020)

Long non-coding RNA MALAT1 enhances the apoptosis of cardiomyocytes through autophagy inhibition by regulating TSC2-mTOR signaling
por: Hu, Hao, et al.
Publicado: (2019)

Dexmedetomidine Protects Against Oxygen–Glucose Deprivation-Induced Injury Through Inducing Astrocytes Autophagy via TSC2/mTOR Pathway
por: Zhu, Chen, et al.
Publicado: (2019)

Long non-coding RNA MEG3 promotes cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagy
por: Jing, Xu, et al.
Publicado: (2021)

TBK1 Mediates Innate Antiviral Immune Response against Duck Enteritis Virus
por: Wang, Dongfang, et al.
Publicado: (2022)

Non-Structural Protein 3 of Duck Tembusu Virus Induces Autophagy via the ERK and PI3K–AKT–mTOR Signaling Pathways
por: Zhao, Jun, et al.
Publicado: (2022)

Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling
por: Tu, Yue, et al.
Publicado: (2017)

Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling
por: Sun, Dongdong, et al.
Publicado: (2020)

Trimetazidine ameliorates sunitinib-induced cardiotoxicity in mice via the AMPK/mTOR/autophagy pathway
por: Yang, Yi, et al.
Publicado: (2019)

AMPK/mTOR Signaling in Autophagy Regulation During Cisplatin-Induced Acute Kidney Injury
por: Wang, Ying, et al.
Publicado: (2020)

Recombinant Duck Enteritis Virus-Vectored Bivalent Vaccine Effectively Protects Against Duck Hepatitis A Virus Infection in Ducks
por: Yang, Fuchun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_odfaj96d8l8d86rcnlbearft8j