Rapid generation of Col7a1(−/−) mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

Recessive dystrophic epidermolysis bullosa (RDEB) is a debilitating and ultimately lethal blistering disease caused by mutations to the Col7a1(−/−) gene. Development of novel cell therapies for the treatment of RDEB would be fostered by having immunodeficient mouse models able to accept human cell g...

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Detalles Bibliográficos
Autores principales: Webber, Beau R., O’Connor, Kyle T., McElmurry, Ron T., Durgin, Elise N., Eide, Cindy, Lees, Christopher J., Riddle, Megan J., Mathews, Wendy, Frank, Natasha Y., Kluth, Mark A., Ganss, Christoph, Moriarity, Branden S., Frank, Markus H., Osborn, Mark J., Tolar, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623156/
https://www.ncbi.nlm.nih.gov/pubmed/28892093
http://dx.doi.org/10.1038/labinvest.2017.85

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