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The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study
OBJECTIVE: To assess the diagnostic accuracy of peripheral capillary oxygen saturation (SpO(2)) while breathing room air for 5 min (the ‘Air-Test’) in detecting postoperative atelectasis. DESIGN: Prospective cohort study. Diagnostic accuracy was assessed by measuring the agreement between the index...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Open
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623366/ https://www.ncbi.nlm.nih.gov/pubmed/28554935 http://dx.doi.org/10.1136/bmjopen-2016-015560 |
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author | Ferrando, Carlos Romero, Carolina Tusman, Gerardo Suarez-Sipmann, Fernando Canet, Jaume Dosdá, Rosa Valls, Paola Villena, Abigail Serralta, Ferran Jurado, Ana Carrizo, Juan Navarro, Jose Parrilla, Cristina Romero, Jose E Pozo, Natividad Soro, Marina Villar, Jesús Belda, Francisco Javier |
author_facet | Ferrando, Carlos Romero, Carolina Tusman, Gerardo Suarez-Sipmann, Fernando Canet, Jaume Dosdá, Rosa Valls, Paola Villena, Abigail Serralta, Ferran Jurado, Ana Carrizo, Juan Navarro, Jose Parrilla, Cristina Romero, Jose E Pozo, Natividad Soro, Marina Villar, Jesús Belda, Francisco Javier |
author_sort | Ferrando, Carlos |
collection | PubMed |
description | OBJECTIVE: To assess the diagnostic accuracy of peripheral capillary oxygen saturation (SpO(2)) while breathing room air for 5 min (the ‘Air-Test’) in detecting postoperative atelectasis. DESIGN: Prospective cohort study. Diagnostic accuracy was assessed by measuring the agreement between the index test and the reference standard CT scan images. SETTING: Postanaesthetic care unit in a tertiary hospital in Spain. PARTICIPANTS: Three hundred and fifty patients from 12 January to 7 February 2015; 170 patients scheduled for surgery under general anaesthesia who were admitted into the postsurgical unit were included. INTERVENTION: The Air-Test was performed in conscious extubated patients after a 30 min stabilisation period during which they received supplemental oxygen therapy via a venturi mask. The Air-Test was defined as positive when SpO(2) was ≤96% and negative when SpO(2) was ≥97%. Arterial blood gases were measured in all patients at the end of the Air-Test. In the subsequent 25 min, the presence of atelectasis was evaluated by performing a CT scan in 59 randomly selected patients. MAIN OUTCOME MEASURES: The primary study outcome was assessment of the accuracy of the Air-Test for detecting postoperative atelectasis compared with the reference standard. The secondary outcome was the incidence of positive Air-Test results. RESULTS: The Air-Test diagnosed postoperative atelectasis with an area under the receiver operating characteristic curve of 0.90 (95% CI 0.82 to 0.98) with a sensitivity of 82.6% and a specificity of 87.8%. The presence of atelectasis was confirmed by CT scans in all patients (30/30) with positive and in 5 patients (17%) with negative Air-Test results. Based on the Air-Test, postoperative atelectasis was present in 36% of the patients (62 out of 170). CONCLUSION: The Air-Test may represent an accurate, simple, inexpensive and non-invasive method for diagnosing postoperative atelectasis. TRIAL REGISTRATION: NCT02650037. |
format | Online Article Text |
id | pubmed-5623366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BMJ Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-56233662017-10-10 The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study Ferrando, Carlos Romero, Carolina Tusman, Gerardo Suarez-Sipmann, Fernando Canet, Jaume Dosdá, Rosa Valls, Paola Villena, Abigail Serralta, Ferran Jurado, Ana Carrizo, Juan Navarro, Jose Parrilla, Cristina Romero, Jose E Pozo, Natividad Soro, Marina Villar, Jesús Belda, Francisco Javier BMJ Open Anaesthesia OBJECTIVE: To assess the diagnostic accuracy of peripheral capillary oxygen saturation (SpO(2)) while breathing room air for 5 min (the ‘Air-Test’) in detecting postoperative atelectasis. DESIGN: Prospective cohort study. Diagnostic accuracy was assessed by measuring the agreement between the index test and the reference standard CT scan images. SETTING: Postanaesthetic care unit in a tertiary hospital in Spain. PARTICIPANTS: Three hundred and fifty patients from 12 January to 7 February 2015; 170 patients scheduled for surgery under general anaesthesia who were admitted into the postsurgical unit were included. INTERVENTION: The Air-Test was performed in conscious extubated patients after a 30 min stabilisation period during which they received supplemental oxygen therapy via a venturi mask. The Air-Test was defined as positive when SpO(2) was ≤96% and negative when SpO(2) was ≥97%. Arterial blood gases were measured in all patients at the end of the Air-Test. In the subsequent 25 min, the presence of atelectasis was evaluated by performing a CT scan in 59 randomly selected patients. MAIN OUTCOME MEASURES: The primary study outcome was assessment of the accuracy of the Air-Test for detecting postoperative atelectasis compared with the reference standard. The secondary outcome was the incidence of positive Air-Test results. RESULTS: The Air-Test diagnosed postoperative atelectasis with an area under the receiver operating characteristic curve of 0.90 (95% CI 0.82 to 0.98) with a sensitivity of 82.6% and a specificity of 87.8%. The presence of atelectasis was confirmed by CT scans in all patients (30/30) with positive and in 5 patients (17%) with negative Air-Test results. Based on the Air-Test, postoperative atelectasis was present in 36% of the patients (62 out of 170). CONCLUSION: The Air-Test may represent an accurate, simple, inexpensive and non-invasive method for diagnosing postoperative atelectasis. TRIAL REGISTRATION: NCT02650037. BMJ Open 2017-05-29 /pmc/articles/PMC5623366/ /pubmed/28554935 http://dx.doi.org/10.1136/bmjopen-2016-015560 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Anaesthesia Ferrando, Carlos Romero, Carolina Tusman, Gerardo Suarez-Sipmann, Fernando Canet, Jaume Dosdá, Rosa Valls, Paola Villena, Abigail Serralta, Ferran Jurado, Ana Carrizo, Juan Navarro, Jose Parrilla, Cristina Romero, Jose E Pozo, Natividad Soro, Marina Villar, Jesús Belda, Francisco Javier The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study |
title | The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study |
title_full | The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study |
title_fullStr | The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study |
title_full_unstemmed | The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study |
title_short | The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study |
title_sort | accuracy of postoperative, non-invasive air-test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study |
topic | Anaesthesia |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623366/ https://www.ncbi.nlm.nih.gov/pubmed/28554935 http://dx.doi.org/10.1136/bmjopen-2016-015560 |
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