Application of pharmacogenomics to investigate adverse drug reactions to the disease-modifying treatments for multiple sclerosis: a case–control study protocol for dimethyl fumarate-induced lymphopenia

INTRODUCTION: Adverse drug reactions (ADRs) are a global public health issue. The potential for pharmacogenomic biomarkers has been demonstrated in several therapeutical areas, including HIV infection and oncology. Dimethyl fumarate (DMF) is a licensed disease-modifying therapy for the treatment of...

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Detalles Bibliográficos
Autores principales: Kowalec, Kaarina, Kingwell, Elaine, Carruthers, Robert, Marrie, Ruth Ann, Bernatsky, Sasha, Traboulsee, Anthony, Ross, Colin J D, Carleton, Bruce, Tremlett, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623385/
https://www.ncbi.nlm.nih.gov/pubmed/28576902
http://dx.doi.org/10.1136/bmjopen-2017-016276

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