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Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus

The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV). Similar to NPCs derived from striatum of day 1 postnatal GFP-transgenic mice (GFP-NPCs), iPSC-...

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Detalles Bibliográficos
Autores principales: Mangale, Vrushali, Marro, Brett S., Plaisted, Warren C., Walsh, Craig M., Lane, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623645/
https://www.ncbi.nlm.nih.gov/pubmed/28822268
http://dx.doi.org/10.1016/j.virol.2017.08.003