Lack of interleukin‐6 in the tumor microenvironment augments type‐1 immunity and increases the efficacy of cancer immunotherapy

Conquering immunosuppression in tumor microenvironments is crucial for effective cancer immunotherapy. It is well known that interleukin (IL)‐6, a pleiotropic cytokine, is produced in the tumor‐bearing state. In the present study, we investigated the precise effects of IL‐6 on antitumor immunity and...

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Detalles Bibliográficos
Autores principales: Ohno, Yosuke, Toyoshima, Yujiro, Yurino, Hideaki, Monma, Norikazu, Xiang, Huihui, Sumida, Kentaro, Kaneumi, Shun, Terada, Satoshi, Hashimoto, Shinichi, Ikeo, Kazuho, Homma, Shigenori, Kawamura, Hideki, Takahashi, Norihiko, Taketomi, Akinobu, Kitamura, Hidemitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623732/
https://www.ncbi.nlm.nih.gov/pubmed/28746799
http://dx.doi.org/10.1111/cas.13330

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