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Interleukin‐6/STAT3 signaling as a promising target to improve the efficacy of cancer immunotherapy

Overcoming the immunosuppressive state in tumor microenvironments is a critical issue for improving the efficacy of cancer immunotherapy. Interleukin (IL)‐6, a pleiotropic cytokine, is highly produced in the tumor‐bearing host. Previous studies have indicated that IL‐6 suppresses the antigen present...

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Detalles Bibliográficos
Autores principales: Kitamura, Hidemitsu, Ohno, Yosuke, Toyoshima, Yujiro, Ohtake, Junya, Homma, Shigenori, Kawamura, Hideki, Takahashi, Norihiko, Taketomi, Akinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623748/
https://www.ncbi.nlm.nih.gov/pubmed/28749573
http://dx.doi.org/10.1111/cas.13332