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Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation

BACKGROUND: Blepharospasm can be present as an isolated dystonia or in conjunction with other forms of cranial dystonia, causing significant disability. CASE REPORT: We report a case of a 69-year-old male with craniocervical dystonia, manifesting primarily as incapacitating blepharospasm refractory...

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Autores principales: Luthra, Nijee S., Mitchell, Kyle T., Volz, Monica M., Tamir, Idit, Starr, Phillip A., Ostrem, Jill L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Columbia University Libraries/Information Services 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623756/
https://www.ncbi.nlm.nih.gov/pubmed/28975046
http://dx.doi.org/10.7916/D8SJ1V9F
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author Luthra, Nijee S.
Mitchell, Kyle T.
Volz, Monica M.
Tamir, Idit
Starr, Phillip A.
Ostrem, Jill L.
author_facet Luthra, Nijee S.
Mitchell, Kyle T.
Volz, Monica M.
Tamir, Idit
Starr, Phillip A.
Ostrem, Jill L.
author_sort Luthra, Nijee S.
collection PubMed
description BACKGROUND: Blepharospasm can be present as an isolated dystonia or in conjunction with other forms of cranial dystonia, causing significant disability. CASE REPORT: We report a case of a 69-year-old male with craniocervical dystonia, manifesting primarily as incapacitating blepharospasm refractory to medical treatments. He underwent bilateral globus pallidus (GP) deep brain stimulation (DBS) with complete resolution of his blepharospasm and sustained benefit at 12 months postoperatively. DISCUSSION: This case illustrates successful treatment of blepharospasm with pallidal stimulation. GP-DBS should be considered a reasonable therapeutic option for intractable blepharospasm.
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spelling pubmed-56237562017-10-03 Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation Luthra, Nijee S. Mitchell, Kyle T. Volz, Monica M. Tamir, Idit Starr, Phillip A. Ostrem, Jill L. Tremor Other Hyperkinet Mov (N Y) Case Reports BACKGROUND: Blepharospasm can be present as an isolated dystonia or in conjunction with other forms of cranial dystonia, causing significant disability. CASE REPORT: We report a case of a 69-year-old male with craniocervical dystonia, manifesting primarily as incapacitating blepharospasm refractory to medical treatments. He underwent bilateral globus pallidus (GP) deep brain stimulation (DBS) with complete resolution of his blepharospasm and sustained benefit at 12 months postoperatively. DISCUSSION: This case illustrates successful treatment of blepharospasm with pallidal stimulation. GP-DBS should be considered a reasonable therapeutic option for intractable blepharospasm. Columbia University Libraries/Information Services 2017-07-06 /pmc/articles/PMC5623756/ /pubmed/28975046 http://dx.doi.org/10.7916/D8SJ1V9F Text en © 2017 Luthra et al. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommerical–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original author and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed.
spellingShingle Case Reports
Luthra, Nijee S.
Mitchell, Kyle T.
Volz, Monica M.
Tamir, Idit
Starr, Phillip A.
Ostrem, Jill L.
Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation
title Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation
title_full Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation
title_fullStr Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation
title_full_unstemmed Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation
title_short Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation
title_sort intractable blepharospasm treated with bilateral pallidal deep brain stimulation
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623756/
https://www.ncbi.nlm.nih.gov/pubmed/28975046
http://dx.doi.org/10.7916/D8SJ1V9F
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