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Novel molecular mechanism of cellular transformation by a mutant molecular chaperone in myeloproliferative neoplasms
Deregulation of the cytokine‐receptor signaling pathway plays a significant role in tumorigenesis. Such deregulation is frequently caused by alterations in the genes involved in the signaling pathway. At the end of 2013, recurrent somatic mutations in the calreticulin (CALR) gene that encodes a mole...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623763/ https://www.ncbi.nlm.nih.gov/pubmed/28741795 http://dx.doi.org/10.1111/cas.13327 |