Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness

Yueju pill is a traditional Chinese medicine formulated to treat syndromes of mood disorders. Here, we investigated the therapeutic effect of repeated low dose of Yueju in the animal model mimicking clinical long-term depression condition and the role of neural plasticity associated with PKA- (prote...

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Detalles Bibliográficos
Autores principales: Zou, Zhilu, Chen, Yin, Shen, Qinqin, Guo, Xiaoyan, Zhang, Yuxuan, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623799/
https://www.ncbi.nlm.nih.gov/pubmed/29075536
http://dx.doi.org/10.1155/2017/9160515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623799/
https://www.ncbi.nlm.nih.gov/pubmed/29075536
http://dx.doi.org/10.1155/2017/9160515

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