PRAS40 promotes NF-κB transcriptional activity through association with p65

PRAS40 has been shown to have a crucial role in the repression of mammalian target of rapamycin (mTOR). Nonetheless, PRAS40 appears to have an oncogenic function in cancer cells. Whether PRAS40 mediates signaling independent of mTOR inhibition in cancer cells remains elusive. Here PRAS40 overexpress...

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Detalles Bibliográficos
Autores principales: Zhu, G, Qi, Q, Havel, J J, Li, Z, Du, Y, Zhang, X, Fu, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623906/
https://www.ncbi.nlm.nih.gov/pubmed/28945219
http://dx.doi.org/10.1038/oncsis.2017.80

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623906/
https://www.ncbi.nlm.nih.gov/pubmed/28945219
http://dx.doi.org/10.1038/oncsis.2017.80

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