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Gene expression signature predicts human islet integrity and transplant functionality in diabetic mice

There is growing evidence that transplantation of cadaveric human islets is an effective therapy for type 1 diabetes. However, gauging the suitability of islet samples for clinical use remains a challenge. We hypothesized that islet quality is reflected in the expression of specific genes. Therefore...

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Detalles Bibliográficos
Autores principales:	Kurian, Sunil M., Ferreri, Kevin, Wang, Chia-Hao, Todorov, Ivan, Al-Abdullah, Ismail H., Rawson, Jeffrey, Mullen, Yoko, Salomon, Daniel R., Kandeel, Fouad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624587/ https://www.ncbi.nlm.nih.gov/pubmed/28968432 http://dx.doi.org/10.1371/journal.pone.0185331

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