MicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response

Cell fate regulation is an open problem whose comprehension impacts several areas of the biosciences. DNA damage induces cell cycle checkpoints that activate the p53 pathway to regulate cell fate mechanisms such as apoptosis or senescence. Experiments with different cell types show that the p53 path...

Descripción completa

Detalles Bibliográficos
Autores principales: Issler, Maria Vitória C., Mombach, José Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624635/
https://www.ncbi.nlm.nih.gov/pubmed/28968438
http://dx.doi.org/10.1371/journal.pone.0185794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624635/
https://www.ncbi.nlm.nih.gov/pubmed/28968438
http://dx.doi.org/10.1371/journal.pone.0185794

Ejemplares similares