IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection

Guanylate binding proteins (GBPs) are interferon-inducible proteins involved in the cell-intrinsic immunity against numerous intracellular pathogens. The molecular mechanisms underlying the potent antibacterial activity of GBPs are still unclear. GBPs have been functionally linked to the NLRP3, the...

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Detalles Bibliográficos
Autores principales: Wallet, Pierre, Benaoudia, Sacha, Mosnier, Amandine, Lagrange, Brice, Martin, Amandine, Lindgren, Helena, Golovliov, Igor, Michal, Fanny, Basso, Pauline, Djebali, Sophia, Provost, Angelina, Allatif, Omran, Meunier, Etienne, Broz, Petr, Yamamoto, Masahiro, Py, Bénédicte F., Faudry, Eric, Sjöstedt, Anders, Henry, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624647/
https://www.ncbi.nlm.nih.gov/pubmed/28968459
http://dx.doi.org/10.1371/journal.ppat.1006630

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