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Pancreatic Carcinoma: the Disease that Kills
The purpose of this case report is to demonstrate the clinical symptoms and laboratory changes that have occurred very late and were very few in number even the imaging studies performed at that time showed an intensive local tumor growth associated with the wide infiltration of the both adjacent an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624683/ https://www.ncbi.nlm.nih.gov/pubmed/28983357 http://dx.doi.org/10.14740/wjon954w |
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author | Kabashi, Serbeze Dedushi, Kreshnike Ramadani, Naser Mucaj, Sefedin Hoxhaj, Asrtrit Jerliu, Naim |
author_facet | Kabashi, Serbeze Dedushi, Kreshnike Ramadani, Naser Mucaj, Sefedin Hoxhaj, Asrtrit Jerliu, Naim |
author_sort | Kabashi, Serbeze |
collection | PubMed |
description | The purpose of this case report is to demonstrate the clinical symptoms and laboratory changes that have occurred very late and were very few in number even the imaging studies performed at that time showed an intensive local tumor growth associated with the wide infiltration of the both adjacent and distant upper abdominal structures. A 71-year-old male patient who was a chronic alcohol abuser and ex smoker (quit smoking 8 years earlier) presented with symptoms of mild pain on epigastric region that irradiated toward the back and significant weight loss. The initial ultrasonography (US) examination was performed, followed by the lab tests and multidetector computed tomography (MDCT) examination. The diagnostic studies confirmed the presence of the pancreatic’s body mass. The ordered laparoscopic evaluation established definitive diagnosis. Initial US examination showed heterogeneous pseudo-cystic changes and slight edema of the pancreatic parenchyma associated with the multiple oval hyperechogenic lesions of liver - the signs highly suggestive of secondary metastatic deposits. The other imaging findings that were obtained with the use of the MDCT confirmed the presence of an expansive primary process of the body of the pancreas associated with the secondary metastatic changes in liver. In addition, the consecutive lymphadenopathy was revealed along hepatoduodenal ligament, retropancreatic region and intraperitoneal compartment. Tumor markers resulted with the high values of the AFP of 2.3, CA19-9 of 423.0 U/mL, and CEA of 219.0 ng/mL. The specimen of the tumor tissue taken during laparoscopic biopsy was sent for histologic examination and the final result was “metastatic adenocarcinoma of pancreas”. Pancreatic body carcinoma has always been associated with poor prognosis because diagnosis is made at the advanced stage of the disease. Therefore, poor prognosis might be improved if early diagnosis could be made. Recent researches confirmed genetic predisposition for this disease at certain group of patients and this “high risk” group has to be followed up with regular imaging studies and lab analysis. |
format | Online Article Text |
id | pubmed-5624683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56246832017-10-05 Pancreatic Carcinoma: the Disease that Kills Kabashi, Serbeze Dedushi, Kreshnike Ramadani, Naser Mucaj, Sefedin Hoxhaj, Asrtrit Jerliu, Naim World J Oncol Case Report The purpose of this case report is to demonstrate the clinical symptoms and laboratory changes that have occurred very late and were very few in number even the imaging studies performed at that time showed an intensive local tumor growth associated with the wide infiltration of the both adjacent and distant upper abdominal structures. A 71-year-old male patient who was a chronic alcohol abuser and ex smoker (quit smoking 8 years earlier) presented with symptoms of mild pain on epigastric region that irradiated toward the back and significant weight loss. The initial ultrasonography (US) examination was performed, followed by the lab tests and multidetector computed tomography (MDCT) examination. The diagnostic studies confirmed the presence of the pancreatic’s body mass. The ordered laparoscopic evaluation established definitive diagnosis. Initial US examination showed heterogeneous pseudo-cystic changes and slight edema of the pancreatic parenchyma associated with the multiple oval hyperechogenic lesions of liver - the signs highly suggestive of secondary metastatic deposits. The other imaging findings that were obtained with the use of the MDCT confirmed the presence of an expansive primary process of the body of the pancreas associated with the secondary metastatic changes in liver. In addition, the consecutive lymphadenopathy was revealed along hepatoduodenal ligament, retropancreatic region and intraperitoneal compartment. Tumor markers resulted with the high values of the AFP of 2.3, CA19-9 of 423.0 U/mL, and CEA of 219.0 ng/mL. The specimen of the tumor tissue taken during laparoscopic biopsy was sent for histologic examination and the final result was “metastatic adenocarcinoma of pancreas”. Pancreatic body carcinoma has always been associated with poor prognosis because diagnosis is made at the advanced stage of the disease. Therefore, poor prognosis might be improved if early diagnosis could be made. Recent researches confirmed genetic predisposition for this disease at certain group of patients and this “high risk” group has to be followed up with regular imaging studies and lab analysis. Elmer Press 2016-02 2016-04-03 /pmc/articles/PMC5624683/ /pubmed/28983357 http://dx.doi.org/10.14740/wjon954w Text en Copyright 2016, Kabashi et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kabashi, Serbeze Dedushi, Kreshnike Ramadani, Naser Mucaj, Sefedin Hoxhaj, Asrtrit Jerliu, Naim Pancreatic Carcinoma: the Disease that Kills |
title | Pancreatic Carcinoma: the Disease that Kills |
title_full | Pancreatic Carcinoma: the Disease that Kills |
title_fullStr | Pancreatic Carcinoma: the Disease that Kills |
title_full_unstemmed | Pancreatic Carcinoma: the Disease that Kills |
title_short | Pancreatic Carcinoma: the Disease that Kills |
title_sort | pancreatic carcinoma: the disease that kills |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624683/ https://www.ncbi.nlm.nih.gov/pubmed/28983357 http://dx.doi.org/10.14740/wjon954w |
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