Cargando…

Effect of MTHFR Polymorphisms on Gastrointestinal Cancer Risk in Italy

BACKGROUND: The aim of the study was to assess the association of single nucleotide polymorphisms (SNPs) C677T and A1298C in the methylenetetrahydrofolate reductase gene with colorectal, esophageal/gastric and pancreatic cancer in a cohort of Italian patients. METHODS: A total of 790 cancer patients...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mazzuca, Federica, Borro, Marina, Botticelli, Andrea, Aimati, Laura, Gentile, Giovanna, Capalbo, Carlo, Maddalena, Chiara, Mazzotti, Eva, Simmaco, Maurizio, Marchetti, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elmer Press 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624687/ https://www.ncbi.nlm.nih.gov/pubmed/28983337 http://dx.doi.org/10.14740/wjon930w

Ejemplares similares

FCGRs Polymorphisms and Response to Trastuzumab in Patients With HER2-Positive Breast Cancer: Far From Predictive Value?
por: Botticelli, Andrea, et al.
Publicado: (2015)

Pre-treatment evaluation of 5-fluorouracil degradation rate: association of poor and ultra-rapid metabolism with severe toxicity in a colorectal cancer patients cohort
por: Mazzuca, Federica, et al.
Publicado: (2016)

Pre-treatment assay of 5-fluorouracil degradation rate (5-FUDR) to improve prediction of 5-fluorouracil toxicity in gastro-esophageal cancer
por: Borro, Marina, et al.
Publicado: (2016)

Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker?
por: Botticelli, Andrea, et al.
Publicado: (2016)

Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine
por: Gentile, Giovanna, et al.
Publicado: (2010)

Frequencies of genetic polymorphisms related to triptans metabolism in chronic migraine
por: Gentile, Giovanna, et al.
Publicado: (2010)

Integrated OMICS tools for personalised medicine
por: Borro, Marina, et al.
Publicado: (2015)

The Exponential Phase of the Covid-19 Pandemic in Central Italy: An Integrated Care Pathway
por: Capalbo, Carlo, et al.
Publicado: (2020)

Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC?
por: Botticelli, Andrea, et al.
Publicado: (2018)

Validation of a small-size pooling approach targeting hospital surveillance of SARS-CoV-2 infection
por: Petrucca, Andrea, et al.
Publicado: (2020)

Frequencies of Combined Dysfunction of Cytochromes P450 2C9, 2C19, and 2D6 in an Italian Cohort: Suggestions for a More Appropriate Medication Prescribing Process
por: Gentile, Giovanna, et al.
Publicado: (2023)

Multiple Chemical Sensitivity Syndrome: A Principal Component Analysis of Symptoms
por: Del Casale, Antonio, et al.
Publicado: (2020)

Evidence-Based Considerations Exploring Relations between SARS-CoV-2 Pandemic and Air Pollution: Involvement of PM2.5-Mediated Up-Regulation of the Viral Receptor ACE-2
por: Borro, Marina, et al.
Publicado: (2020)

Individualized Drugs’ Selection by Evaluation of Drug Properties, Pharmacogenomics and Clinical Parameters: Performance of a Bioinformatic Tool Compared to a Clinically Established Counselling Process
por: Borro, Marina, et al.
Publicado: (2021)

Dopamine DRD2 and DRD3 Polymorphisms Involvement in Nicotine Dependence in Patients with Treatment-Resistant Mental Disorders
por: del Casale, Antonio, et al.
Publicado: (2022)

Drug–Drug Interactions and Pharmacogenomic Evaluation in Colorectal Cancer Patients: The New Drug-PIN(®) System Comprehensive Approach
por: Roberto, Michela, et al.
Publicado: (2021)

No Evidence of SARS-CoV-2 Circulation in Rome (Italy) during the Pre-Pandemic Period: Results of a Retrospective Surveillance
por: Capalbo, Carlo, et al.
Publicado: (2020)

Cross-talk between microbiota and immune fitness to steer and control response to anti PD-1/PDL-1 treatment
por: Botticelli, Andrea, et al.
Publicado: (2016)

Predicting Dihydropyrimidine Dehydrogenase Deficiency and Related 5-Fluorouracil Toxicity: Opportunities and Challenges of DPYD Exon Sequencing and the Role of Phenotyping Assays
por: De Luca, Ottavia, et al.
Publicado: (2022)

Optimising migraine treatment: from drug-drug interactions to personalized medicine
por: Pomes, Leda Marina, et al.
Publicado: (2019)

Combination Therapy of High-Dose Rabeprazole Plus Metronomic Capecitabine in Advanced Gastro-Intestinal Cancer: A Randomized Phase II Trial
por: Roberto, Michela, et al.
Publicado: (2020)

CT based radiomic approach on first line pembrolizumab in lung cancer
por: Zerunian, Marta, et al.
Publicado: (2021)

Pharmacogenomics-Guided Pharmacotherapy in Patients with Major Depressive Disorder or Bipolar Disorder Affected by Treatment-Resistant Depressive Episodes: A Long-Term Follow-Up Study
por: Del Casale, Antonio, et al.
Publicado: (2022)

The Challenge of ICIs Resistance in Solid Tumours: Could Microbiota and Its Diversity Be Our Secret Weapon?
por: Roberto, Michela, et al.
Publicado: (2021)

DRD2, DRD3, and HTR2A Single-Nucleotide Polymorphisms Involvement in High Treatment Resistance to Atypical Antipsychotic Drugs
por: Del Casale, Antonio, et al.
Publicado: (2023)

Lean body mass wasting and toxicity in early breast cancer patients receiving anthracyclines
por: Mazzuca, Federica, et al.
Publicado: (2018)

The Impact of Drug–Drug Interactions on the Toxicity Profile of Combined Treatment with BRAF and MEK Inhibitors in Patients with BRAF-Mutated Metastatic Melanoma
por: Mezi, Silvia, et al.
Publicado: (2023)

MTHFR polymorphisms and breast cancer risk
por: Hosseini, Mojgan, et al.
Publicado: (2011)

The role of stereotactic body radiation therapy in oligometastatic colorectal cancer: Clinical case report of a long-responder patient treated with regorafenib beyond progression
por: Roberto, Michela, et al.
Publicado: (2017)

Clinical Impact of Highly Purified, Whey Proteins in Patients Affected With Colorectal Cancer Undergoing Chemotherapy: Preliminary Results of a Placebo-Controlled Study
por: Mazzuca, Federica, et al.
Publicado: (2019)

Analysis of Short-Term and Stable DNA Damage in Patients with Differentiated Thyroid Cancer Treated with (131)I in Hypothyroidism or with Recombinant Human Thyroid-Stimulating Hormone for Remnant Ablation
por: Signore, Alberto, et al.
Publicado: (2022)

IL28B Gene Polymorphisms and US Liver Fatty Changes in Patients Who Spontaneously Cleared Hepatitis C Virus Infection
por: Taliani, Gloria, et al.
Publicado: (2013)

Electrochemotherapy as Promising Treatment Option in Rare Recurrent Cutaneous Neoplasm of the Scalp: Case Report of an Elderly Patient
por: Crimini, Edoardo, et al.
Publicado: (2019)

SARS-CoV-2 Transmission Control Measures in the Emergency Department: The Role of Rapid Antigenic Testing in Asymptomatic Subjects
por: Borro, Marina, et al.
Publicado: (2022)

Susceptibility to hypertension based on MTHFR rs1801133 single nucleotide polymorphism and MTHFR promoter methylation
por: Chiu, Ming-Huang, et al.
Publicado: (2023)

Association of MTHFR Polymorphisms and Chromosomal Abnormalities in Leukemia
por: Sinthuwiwat, Thivaratana, et al.
Publicado: (2012)

MTHFR polymorphisms in primary varicose vein disorder
por: Fernández-Peralta, Antonia M., et al.
Publicado: (2015)

The association between MTHFR polymorphism and cervical cancer
por: Gong, Jiao-Mei, et al.
Publicado: (2018)

Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphism and Infant’s Anthropometry at Birth
por: Aguilar-Lacasaña, Sofía, et al.
Publicado: (2021)

Human genetic selection on the MTHFR 677C>T polymorphism
por: Mayor-Olea, Álvaro, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_k5u0mjejcbv3t84rm5s1ehp5sh