A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11

Chronic otitis media with effusion (COME) is the most common cause of hearing loss in children, and known to have high heritability. Mutant mouse models have identified Fbxo11, Evi1, Tgif1, and Nisch as potential risk loci. We recruited children aged 10 and under undergoing surgical treatment for CO...

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Detalles Bibliográficos
Autores principales: Bhutta, Mahmood F., Lambie, Jane, Hobson, Lindsey, Goel, Anuj, Hafrén, Lena, Einarsdottir, Elisabet, Mattila, Petri S., Farrall, Martin, Brown, Steve, Burton, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624881/
https://www.ncbi.nlm.nih.gov/pubmed/28970529
http://dx.doi.org/10.1038/s41598-017-12784-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624881/
https://www.ncbi.nlm.nih.gov/pubmed/28970529
http://dx.doi.org/10.1038/s41598-017-12784-8

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