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A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11
Chronic otitis media with effusion (COME) is the most common cause of hearing loss in children, and known to have high heritability. Mutant mouse models have identified Fbxo11, Evi1, Tgif1, and Nisch as potential risk loci. We recruited children aged 10 and under undergoing surgical treatment for CO...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624881/ https://www.ncbi.nlm.nih.gov/pubmed/28970529 http://dx.doi.org/10.1038/s41598-017-12784-8 |