DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1

Stable intronic sequence RNAs (sisRNAs) are by-products of splicing and regulate gene expression. How sisRNAs are regulated is unclear. Here we report that a double-stranded RNA binding protein, Disco-interacting protein 1 (DIP1) regulates sisRNAs in Drosophila. DIP1 negatively regulates the abundan...

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Detalles Bibliográficos
Autores principales: Wong, Jing Ting, Akhbar, Farzanah, Ng, Amanda Yunn Ee, Tay, Mandy Li-Ian, Loi, Gladys Jing En, Pek, Jun Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624886/
https://www.ncbi.nlm.nih.gov/pubmed/28970471
http://dx.doi.org/10.1038/s41467-017-00684-4

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