NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is a clonal disorder of mature B cells. Most patients are characterised by an indolent disease course and an anergic phenotype of their leukaemia cells, which refers to a state of unresponsiveness to B cell receptor stimulation. Up to 10% of CLL patients transform...

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Detalles Bibliográficos
Autores principales: Märklin, Melanie, Heitmann, Jonas S., Fuchs, Alexander R., Truckenmüller, Felicia M., Gutknecht, Michael, Bugl, Stefanie, Saur, Sebastian J., Lazarus, Juliane, Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Rammensee, Hans-Georg, Salih, Helmut R., Kopp, Hans-Georg, Haap, Michael, Kirschniak, Andreas, Kanz, Lothar, Rao, Anjana, Wirths, Stefan, Müller, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624906/
https://www.ncbi.nlm.nih.gov/pubmed/28970470
http://dx.doi.org/10.1038/s41467-017-00830-y

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