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A pathway analysis of genome-wide association study highlights novel type 2 diabetes risk pathways

Genome-wide association studies (GWAS) have been widely used to identify common type 2 diabetes (T2D) variants. However, the known variants just explain less than 20% of the overall estimated genetic contribution to T2D. Pathway-based methods have been applied into T2D GWAS datasets to investigate t...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Zhao, Jing, Jiang, Tao, Yu, Mei, Jiang, Guohua, Hu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624908/
https://www.ncbi.nlm.nih.gov/pubmed/28970525
http://dx.doi.org/10.1038/s41598-017-12873-8

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