Detection of known and novel ALK fusion transcripts in lung cancer patients using next-generation sequencing approaches

Rearrangements of the anaplastic lymphoma kinase (ALK) gene in non-small cell lung cancer (NSCLC) represent a novel molecular target in a small subset of tumors. Although ALK rearrangements are usually assessed by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH), molecular ap...

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Detalles Bibliográficos
Autores principales: Vendrell, Julie A., Taviaux, Sylvie, Béganton, Benoît, Godreuil, Sylvain, Audran, Patricia, Grand, David, Clermont, Estelle, Serre, Isabelle, Szablewski, Vanessa, Coopman, Peter, Mazières, Julien, Costes, Valérie, Pujol, Jean-Louis, Brousset, Pierre, Rouquette, Isabelle, Solassol, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624911/
https://www.ncbi.nlm.nih.gov/pubmed/28970558
http://dx.doi.org/10.1038/s41598-017-12679-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624911/
https://www.ncbi.nlm.nih.gov/pubmed/28970558
http://dx.doi.org/10.1038/s41598-017-12679-8

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