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Detection of known and novel ALK fusion transcripts in lung cancer patients using next-generation sequencing approaches

Rearrangements of the anaplastic lymphoma kinase (ALK) gene in non-small cell lung cancer (NSCLC) represent a novel molecular target in a small subset of tumors. Although ALK rearrangements are usually assessed by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH), molecular ap...

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Detalles Bibliográficos
Autores principales:	Vendrell, Julie A., Taviaux, Sylvie, Béganton, Benoît, Godreuil, Sylvain, Audran, Patricia, Grand, David, Clermont, Estelle, Serre, Isabelle, Szablewski, Vanessa, Coopman, Peter, Mazières, Julien, Costes, Valérie, Pujol, Jean-Louis, Brousset, Pierre, Rouquette, Isabelle, Solassol, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624911/ https://www.ncbi.nlm.nih.gov/pubmed/28970558 http://dx.doi.org/10.1038/s41598-017-12679-8

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