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Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis
Nucleic acids, which constitute the genetic material of all organisms, are continuously exposed to endogenous and exogenous damaging agents, representing a significant challenge to genome stability and genome integrity over the life of a cell or organism. Unrepaired DNA lesions, such as single- and...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624938/ https://www.ncbi.nlm.nih.gov/pubmed/28970491 http://dx.doi.org/10.1038/s41598-017-12662-3 |