The FXR Agonist, Obeticholic Acid, Suppresses HCC Proliferation & Metastasis: Role of IL-6/STAT3 Signalling Pathway

The nuclear receptor, farnesoid X receptor (FXR), has been recently considered as a tumor suppressor in HCC. IL-6/Janus kinase 2 (Jak-2)/signal transducer and activator of transcription 3 (STAT3) pathway has been implicated as a key player in many cancer types. This study aimed at investigating the...

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Detalles Bibliográficos
Autores principales: Attia, Yasmeen M., Tawfiq, Rasha A., Ali, Aya A., Elmazar, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624958/
https://www.ncbi.nlm.nih.gov/pubmed/28970500
http://dx.doi.org/10.1038/s41598-017-12629-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624958/
https://www.ncbi.nlm.nih.gov/pubmed/28970500
http://dx.doi.org/10.1038/s41598-017-12629-4

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