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Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

Direct neuronal reprogramming, by which a neuron is formed via direct conversion from a somatic cell without going through a pluripotent intermediate stage, allows for the possibility of generating patient-derived neurons. A unique feature of these so-called induced neurons (iNs) is the potential to...

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Detalles Bibliográficos
Autores principales: Drouin-Ouellet, Janelle, Pircs, Karolina, Barker, Roger A., Jakobsson, Johan, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625013/
https://www.ncbi.nlm.nih.gov/pubmed/29033781
http://dx.doi.org/10.3389/fnins.2017.00530