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Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3

The kinase p38α MAPK (p38α) plays a pivotal role in many biological processes. p38α is activated by canonical upstream kinases that phosphorylate the activation region. The purpose of our study was to determine whether such activation may depend on redox-sensing cysteines within p38α. p38α was activ...

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Detalles Bibliográficos
Autores principales:	Bassi, Rekha, Burgoyne, Joseph R., DeNicola, Gian F., Rudyk, Olena, DeSantis, Vittorio, Charles, Rebecca L., Eaton, Philip, Marber, Michael S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625047/ https://www.ncbi.nlm.nih.gov/pubmed/28739872 http://dx.doi.org/10.1074/jbc.M117.785410

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