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Plasma cholesterol level determines in vivo prion propagation

Transmissible spongiform encephalopathies are fatal neurodegenerative diseases with an urgent need for therapeutic and prophylactic strategies. At the time when the blood-mediated transmission of prions was demonstrated, in vitro studies indicated a high binding affinity of the scrapie prion protein...

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Detalles Bibliográficos
Autores principales:	Perrier, Véronique, Imberdis, Thibaud, Lafon, Pierre-André, Cefis, Marina, Wang, Yunyun, Huetter, Elisabeth, Arnaud, Jacques-Damien, Alvarez-Martinez, Teresa, Le Guern, Naig, Maquart, Guillaume, Lagrost, Laurent, Desrumaux, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625119/ https://www.ncbi.nlm.nih.gov/pubmed/28765208 http://dx.doi.org/10.1194/jlr.M073718

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