The reversible P2Y(12) antagonist ACT‐246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in rat

The P2Y(12) receptor is a validated target for prevention of major adverse cardiovascular events in patients with acute coronary syndrome. The aim of this study was to compare two direct‐acting, reversible P2Y(12) antagonists, ACT‐246475 and ticagrelor, in a rat thrombosis model by simultaneous quan...

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Detalles Bibliográficos
Autores principales: Rey, Markus, Kramberg, Markus, Hess, Patrick, Morrison, Keith, Ernst, Roland, Haag, Franck, Weber, Edgar, Clozel, Martine, Baumann, Martine, Caroff, Eva, Hubler, Francis, Riederer, Markus A., Steiner, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625150/
https://www.ncbi.nlm.nih.gov/pubmed/28805949
http://dx.doi.org/10.1002/prp2.338

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