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17β‐estradiol reduces Ca(v)1.2 channel abundance and attenuates Ca(2+)‐dependent contractions in coronary arteries

One mechanism by which the female sex may protect against elevated coronary vascular tone is inhibition of Ca(2+) entry into arterial smooth muscle cells (ASMCs). In vitro findings confirm that high estrogen concentrations directly inhibit voltage‐dependent Ca(v)1.2 channels in coronary ASMCs. For t...

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Detalles Bibliográficos
Autores principales:	Hill, Brent J.F., Dalton, Robin J., Joseph, Biny K., Thakali, Keshari M., Rusch, Nancy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625162/ https://www.ncbi.nlm.nih.gov/pubmed/28971605 http://dx.doi.org/10.1002/prp2.358

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