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Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients

Background: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Various genetic and epigenetic factors have been found to be influential in such patients. Methylation silencing of APAF-1, a putative tumor suppr...

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Detalles Bibliográficos
Autores principales:	Rostami, Shahrbano, Nadali, Fatemeh, Alibakhshi, Reza, Zaker, Farhad, Nasiri, Nahid, Payandeh, Mehrdad, Chahardouli, Bahram, Maleki, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625473/ https://www.ncbi.nlm.nih.gov/pubmed/28989589

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