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Inactivated H7 Influenza Virus Vaccines Protect Mice despite Inducing Only Low Levels of Neutralizing Antibodies

Avian influenza viruses of the H7 hemagglutinin (HA) subtype present a significant public health threat, as evidenced by the ongoing outbreak of human A(H7N9) infections in China. When evaluated by hemagglutination inhibition (HI) and microneutralization (MN) assays, H7 viruses and vaccines are foun...

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Detalles Bibliográficos
Autores principales: Kamal, Ram P., Blanchfield, Kristy, Belser, Jessica A., Music, Nedzad, Tzeng, Wen-Pin, Holiday, Crystal, Burroughs, Ashley, Sun, Xiangjie, Maines, Taronna R., Levine, Min Z., York, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625511/
https://www.ncbi.nlm.nih.gov/pubmed/28768855
http://dx.doi.org/10.1128/JVI.01202-17